Thyroid Tests: What Do the Numbers Mean?

Your lab results came back normal, but you still don’t feel like yourself

You finally got bloodwork.
You waited, hoping it would explain the brain fog.
The fatigue.
The weight gain.
The cold hands.
The mood swings.
Your doctor says, “Everything looks fine.”
But you don’t feel fine.
Not even close.
And that’s where thyroid numbers start to matter more than they seem.

TSH tells part of the story, but not the whole

Thyroid-stimulating hormone comes from the pituitary.
It tells your thyroid to get moving.
When TSH is high, your thyroid might be sluggish.
When it’s low, your thyroid might be overactive.
But it’s just a signal—not the full picture.
You can have symptoms even when TSH is “within range.”
Because what’s normal on paper isn’t always what your body needs.

Free T4 shows what your thyroid actually makes

T4 is the storage form.
Your thyroid sends it out, hoping your cells will convert it later.
It’s inactive—but essential.
Low free T4 means your thyroid’s not keeping up.
High free T4 might mean your body’s working too fast.
But again, if conversion is broken, this number won’t tell you everything.

Free T3 reveals what your body actually uses

T4 becomes T3 in your liver and gut.
T3 is active.
It’s what fuels your cells, your metabolism, your brain.
Low T3?
That’s when you feel slow, heavy, forgetful.
Even if TSH and T4 look fine.
Doctors often skip this test—but it’s the one that speaks your language.

Reverse T3 blocks the message

When you’re stressed, your body makes more reverse T3.
It binds to T3 receptors but doesn’t activate them.
It’s like a fake key—it fits the lock but doesn’t open the door.
High reverse T3 can make you feel hypothyroid.
Even when all your other numbers look perfect.
That’s why it matters.
And why it’s rarely tested.

Thyroid antibodies mean your immune system is involved

TPO and TG antibodies reveal something deeper.
They don’t reflect function.
They reflect attack.
When your immune system targets your thyroid, it’s autoimmune.
Hashimoto’s.
Graves’.
You can have antibodies for years before your TSH changes.
But symptoms may already be there.
Quiet, early, ignored.

You can be “normal” and still not feel normal

Reference ranges are wide.
What’s “normal” for labs isn’t always right for your body.
A TSH of 4.5 might not work for you.
Maybe not even 3.
You feel it in your sleep.
In your skin.
In the space between who you are and how you feel.
Your symptoms are not less real because your numbers look neat.

Conversion problems can mimic thyroid disease

Your thyroid may produce enough T4.
But if your liver or gut can’t convert it to T3, the energy never comes.
You stay tired.
Cold.
Foggy.
But your labs don’t raise alarms.
Because conversion happens after the thyroid.
And most panels don’t check there.

Stress, nutrient deficiencies, and chronic illness all affect your numbers

Low iron can lower T3.
So can low selenium.
Zinc.
Vitamin D.
Stress raises cortisol, which increases reverse T3.
Gut inflammation reduces T4 to T3 conversion.
You’re not broken—you’re just under-supported.
And your thyroid is whispering through every system.

Thyroid panels without context don’t give answers—they give data

Numbers without symptoms don’t mean much.
Symptoms without numbers get dismissed.
The truth lives in the middle.
It’s not just about labs—it’s about listening.
To fatigue.
To anxiety.
To weight gain that doesn’t respond to effort.
To hair loss that doesn’t stop with shampoo.

The right tests matter more than more tests

TSH alone is not enough.
You need free T4.
Free T3.
Reverse T3.
TPO and TG antibodies.
Only then can someone see the whole picture.
Only then do the numbers stop being confusing—and start becoming answers.